Tartaric Acid
Selleck Chemical LLC ENMD-2076 L-()-Tartaric acid S2018-5mg
ENMD-2076 L-( )-Tartaric acid is the tartaric acid of ENMD-2076 selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1 86 nM 25-fold more selective for Aurora A than Aurora B and less potent to VEGFR2/KDR and VEGFR3 FGFR1 and FGFR2 and PDGFR Phase 2
Selleck Chemical LLC ENMD-2076 S1181-10mM/1mL
ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1 86 nM 25-fold selective for Aurora A than over Aurora B and less potent to RET SRC NTRK1/TRKA CSF1R/FMS VEGFR2/KDR FGFR and PDGFR ENMD-2076 inhibits the growth of a wide range of human solid tumor and hematopoietic cancer cell lines with IC50 from 0 025 to 0 7 M which induces apoptosis and G2/M phase arrest Phase 2
Chem-Impex International, Inc. (-)-Dibenzoyl-L-tartaric acid | MFCD00003074 | 25G
(-)-Dibenzoyl-L-tartaric acid, MFCD00003074, 25G
Sigma Aldrich Fine Chemicals Biosciences (-)-O,O'-Dibenzoyl-L-tartaric acid monohydrate >=99.0% (T) | 62708-56-9 | MFCD00149119 | 100G
(-)-O,O'-Dibenzoyl-L-tartaric acid monohydrate >=99.0% (T) | Purity: >=99.0% (T) | Mol Wt: 376.31 | 62708-56-9 | MFCD00149119 | 100G
Medchemexpress LLC R,S-anatabine | 2743-90-0 | MFCD01669938 | 99.7% | 160.22 | C10H12N2 | 100MG
(R,S)-Anatabine is the racemic form of anatabine, a minor tobacco alkaloid supplied as an analytical standard and research reagent for biochemical and analytical applications, including use as a marker of tobacco exposure and in amyloid-beta studies.
- Analytical standard for detection and quantification of tobacco alkaloids.
- Racemic (R,S) form of anatabine.
- Molecular formula C10H12N2; molecular weight 160.22.
- High purity (99.7%).
- Typically supplied as a 100 mg reference material.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Fobrepodacin disodium | 1384984-20-6 | 99.5% | C21H24FN6Na2O6P | 10MG
Fobrepodacin disodium is the disodium phosphate prodrug of an aminobenzimidazole gyrase B/ParE inhibitor. It is an orally bioavailable antibacterial agent that demonstrates potent bactericidal activity in preclinical in vivo models, including mycobacterial infection studies. Supplied as a white to off-white solid, it is intended for research use in drug discovery and efficacy experiments.
- Orally bioavailable phosphate prodrug
- Potent bactericidal activity in vivo
- Suitable for preclinical efficacy and pharmacology studies
- White to off-white solid, convenient for formulation
- High purity (99.5%) for reproducible results
Chem-Impex International, Inc. D(-)-Tartaric acid | 147-71-7 | MFCD00004238 | 100G
D(-)-Tartaric acid, 147-71-7, MFCD00004238, 100G
Apexbio Technology LLC ENMD-2076 934353-76-1 200mg
ENMD-2076 (CAS 934353-76-1) is a selective inhibitor of Aurora A kinase (IC50 14 nM) and FLT3 (IC50 1 86 nM) with additional inhibitory activity against multiple tyrosine kinases implicated in angiogenesis and cell proliferation including RET FLT4/VEGFR3 SRC CSF1R NTRK1 FGFR1/2 VEGFR2/KDR LCK and PDGFR (IC50 1 86 120 nM) ENMD-2076 disrupts cell cycle progression by arresting cells in the G2/M phase through inhibition of Aurora kinases suppresses the PI3K/AKT signaling pathway and demonstrates cytotoxic effects in hematologic malignancy and solid tumor cell lines (in vitro IC50 25 700 nM) In vivo it reduces tumor growth and angiogenesis in xenograft models supporting its use in cancer research and antiangiogenic studies